Green Synthesis of Mimosa pudica-Mediated Strontium Nanoparticles and its Anti-Inflammatory Activity

含羞草介导的锶纳米粒子的绿色合成及其抗炎活性

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Abstract

BACKGROUND: Considerable focus has been directed toward green synthesis as a dependable, sustainable, and environmentally friendly approach for synthesizing various nanomaterials. Mimosa pudica, a quickly grown pantropical weed, has been used widely for its anti-inflammatory and antimicrobial activity in traditional medicine. The development of strontium-based nanoparticles and nanoparticles linked with strontium has garnered attention in recent years due to their established utility in diverse domains such as effective drug distribution, bioimaging, cancer treatment, and advancements in bone engineering. AIMS AND OBJECTIVES: To examine the green synthesise of strontium nanoparticles using Mimosa pudica and its anti-inflammatory activity. MATERIAL AND METHODS: Mimosa pudica-mediated strontium nanoparticles' anti-inflammatory activity was tested using bovine serum albumin denaturation assay, egg albumin denaturation assay, and membrane stabilization assay with diclofenac sodium as the standard. Result: In all three assays, increasing concentration of Mimosa pudica-mediated strontium nanoparticles exhibited an increasing anti-inflammatory effect, which was similar to the standard diclofenac sodium. CONCLUSION: Consequently, this holds promise as a new potential anti-inflammatory agent in forthcoming applications.

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