Proteome remodeling upon disruption of virulence-associated CipC from Cryptococcus neoformans

新型隐球菌毒力相关CipC破坏后蛋白质组的重塑

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Abstract

The human fungal pathogen, Cryptococcus neoformans, produces an array of virulence factors that regulate the production of a polysaccharide capsule and melanin, thermotolerance, and the release of extracellular enzymes. Here, we applied quantitative proteomics to investigate the role of CipC, a known virulence-associated protein, in the fungus.

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