Abstract
Gastrointestinal perforation remains one of the most commonly encountered surgical emergencies. Despite the advancement in surgical techniques and treatment modalities, retroperitoneal duodenal perforation remains a lethal surgical emergency. While perforations of the gastrointestinal tract are typically managed with laparotomy for repair and decontamination, the advancement in endoscopic technique and equipment shed a light on non-operative management for intestinal perforation. We present here a case of duodenal perforation successfully treated by endoscopic approach.