Abstract
The COVID-19 pandemic was an unexpected and disruptive event that significantly affected the performance of manufacturing systems and supply chains in various sectors. In this paper, a literature review is provided, which investigates the role that Industry 4.0 technologies and simulation tools have played in addressing the effects of the pandemic crisis. Specifically, a bibliometric analysis provides an overview of the most influential technologies through a study of the most used keywords. While a document analysis, conducted on critical papers that concern real case studies, shows that so far simulation provided support in four main areas: energy consumption, healthcare supply chain & contact tracing, food supply chain, and in general supply chain management. The main outcome of this research work is that Industry 4.0 technologies and simulation models were particularly important during the pandemic crisis and their properties deserve to be deeply exploited in the near future.