Firstly electrochemical investigetions and determination of anticoagulant drug edoxaban at single-use pencil graphite electrode: an eco-friendly and cost effective voltammetric method

首先在一次性铅笔石墨电极上进行抗凝药物依度沙班的电化学研究和测定:一种环保且经济有效的伏安法

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作者:Abdulkadir Kiliç, Mehmet Aslan, Günay Önal, Abdulkadir Levent

Conclusion

The method developed in this study was successfully applied to drug and urine samples. The developed voltammetric method was highly selective and gave satisfactory recovery results in urine and pharmaceutical samples. The results of the voltammetric method were compared with the spectroscopic method and it was determined that the results were compatible.

Results

This procedure showed a linear response in a Britton-Robinson (pH 9.0) media within the concentration range of 0.2-1.8 µM and limit of detection (LOD) and the limit of quantification (LOQ) values were determined to be 0.073 μM (0.133 μg mL-1) and 0.243 μM (0.443 μg mL-1), respectively.

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