Hearing Loss in a Patient with Waldenstrom Macroglobulinemia Receiving Bortezomib

接受硼替佐米治疗的华氏巨球蛋白血症患者出现听力丧失

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Abstract

INTRODUCTION: We present a case report of hearing loss in a patient with Waldenstrom macroglobulinemia (WM) receiving treatment with bortezomib. CASE PRESENTATION: Our patient developed sudden bilateral sensorineural hearing loss after receiving three doses of bortezomib. His hearing loss was irreversible and resulted in a cochlear implant. CONCLUSION: Hearing loss secondary to bortezomib is a known, but very rare, side effect. Hearing loss secondary to WM is also rare and has been described in case reports.

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