Synthesis, Surface Activity, Emulsifiability and Bactericidal Performance of Zwitterionic Tetrameric Surfactants

两性离子四聚表面活性剂的合成、表面活性、乳化性和杀菌性能

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Abstract

In this paper, a series of tetrameric surfactants (4C(n)SAZs, n = 12, 14, 16) endowed with zwitterionic characteristic were synthesized by a simple and convenient method and their structures were characterized by FT-IR, (1)H NMR and elemental analysis. Their physicochemical properties were studied using the Wilhelmy plate method, fluorescence spectra and dynamic light scattering technique. 4C(n)SAZs have higher surface activities and tend to adsorb at the air/water surface rather than self-assembling in aqueous solution. The thermodynamic parameters obtained from surface tension measurements show that both processes of adsorption and micellization of 4C(n)SAZs are spontaneous and that the micellization processes of 4C(n)SAZs are entropy-driven processes. Both adsorption and micellization of 4C(n)SAZs are inclined to occur with the increase of alkyl chain length or temperature. For 4C(12)SAZs, there are only small-size aggregates (micelles), while the large aggregates (vesicles) are observed at the alkyl length of 4C(n)SAZs of 14 or 16. This shows that the alkyl chain length for oligomeric surfactants has a greater sensitivity for aggregate growth. The aggregate morphologies obtained from the calculated values of critical packing parameter (p) for 4C(14)SAZs and 4C(16)SAZs can be supported by the DLS measurement results. The test results obtained by the separation-water-time method show that 4C(n)SAZs have good emulsification performance and that the prepared emulsions appear to exit in the form of multiple emulsions. In addition, 4C(n)SAZs have good antibacterial activities against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The present study reveals the unique behavior of a zwitterionic tetrameric surfactant and may give new insights into molecular design and synthesis of a high degree of surfactants with different structure characteristics for potential application in various industrial fields.

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