Abstract
Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is an uncommon disease pathology seen in immunocompetent patients. The most common causative fungal agents reported in the literature are members of the Aspergillus species. CGIFRS may be mistaken for sinonasal malignancy because of its invasive pattern. This article reports a case of CGIFRS in an immunocompetent male patient with intracranial extension who responded well to antifungals (liposomal Amphotericin and Itraconazole) after surgical debulking. Appropriate clinicopathological evaluation and diagnosis are essential for proper management. Only a few such cases have been reported in the literature. In the Republic of South Africa, no case of CGIFRS with intracranial extension has been reported prior to this case.