Abstract
Guidelines for managing lower gastrointestinal bleeding (LGIB) can vary significantly, posing challenges in clinical settings. This case involves a previously healthy man who presented with severe acute rectal bleeding, along with COVID-19 positivity, Janeway lesions, and splinter hemorrhages. His condition rapidly deteriorated, with evidence suggesting a diverticular bleed. Treatment with angiography and embolization successfully stabilized him, resulting in an excellent outcome. Accurate diagnosis and stabilization necessitate a coordinated approach tailored to each patient's condition. Early angiography should be considered for initial hemostasis in severe cases of LGIB, as demonstrated in this case.