Abstract
INTRODUCTION: Osteomyelitis due to Cutibacterium acnes in the clavicle without a history of previous surgery is extremely rare and has been reported in one previous study. In this report, we delve into a case of clavicular osteomyelitis caused by C. acnes without the presence of hardware materials. CASE REPORT: We report here a case of a 32-year-old female presented with spontaneous clavicular osteomyelitis due to C. acnes that failed with medical management. The Patient was successfully treated by surgical debridement and calcium sulfate filling that impregnated with local antibiotics. CONCLUSION: This case demonstrates that clavicular osteomyelitis can be caused by C. acnes even without the presence of a device. Therefore, cultures from potential bone infections that yield C. acnes should not be dismissed as contaminants. Combining clinical and laboratory criteria with emerging microbiologic tests may enhance the predictive value of C. acnes diagnostic testing in the future.