Abstract
Shewanella putrefaciens (S. putrefaciens) is a Gram-negative anaerobic organism responsible for opportunistic infections in immunocompromised hosts. It can cause a wide range of infections in humans, including skin and soft tissue infections (SSTIs) and bacteremia. Peripheral vascular disease and the presence of chronic bilateral lower extremity ulcers may serve as risk factors for these infections. This is a case report of an 80-year-old male with a history of peripheral vascular disease and chronic lymphedema of the bilateral lower extremities who presented with generalized weakness. He was found to have septic shock and Shewanella putrefaciens bacteremia secondary to left lower extremity cellulitis. There was no history of exposure to the marine environment. However, the patient had multiple comorbid conditions and chronic denuded skin due to lymphedema, which may have provided a nidus for bacterial proliferation and entry into the bloodstream.