Abstract
Wernicke's encephalopathy (WE) is an acute neurological disorder secondary to thiamine deficiency (vitamin B1). Treatment should be started as early as possible to prevent serious complications. Typical magnetic resonance imaging (MRI) findings of WE can be seen as symmetrical signal abnormalities in the periventricular regions of the thalamus, hypothalamus, mammillary bodies, periaqueductal region, and floor of the fourth ventricle. Intracranial hemorrhage is a rare but serious complication of WE, whose physiopathology remains unclear. We report the case of a 48-year-old man with suggestive MRI abnormalities of WE in typical sites and low serum thiamine levels, complicated by intracerebral hematoma.