Abstract
Endophthalmitis is a rare, vision-threatening ocular infection. During the COVID-19 pandemic, the widespread use of immunosuppressive agents-particularly corticosteroids-and prolonged hospital stays have been associated with an increased risk of secondary bacterial infections, including ocular involvement. One such opportunistic pathogen is Streptococcus pneumoniae. Among the rare but severe complications of endogenous endophthalmitis is retinal detachment (RD), which often results in a poor visual prognosis. We present a unique case of RD secondary to endogenous endophthalmitis in a COVID-19 patient with S. pneumoniae bacteremia. This case highlights the importance of early ophthalmologic evaluation in patients with ocular symptoms during or after COVID-19 infection to ensure timely intervention and improve clinical outcomes.