Abstract
Haemophilus influenzae (Hi) meningitis is a rare but serious bacterial infection in newborns and infants. While type b (Hib) has historically been the most prevalent strain, non-b serotypes remain uncommon and are not well characterized, underscoring the need for accurate identification and serotyping to improve clinical understanding and management. These non-b variants have been increasingly associated with severe neurological complications and poor outcomes, highlighting the importance of early recognition and targeted therapeutic intervention. We report the case of a 23-day-old newborn diagnosed with Hi meningitis caused by a non-b serotype, illustrating the complexities of this rare presentation. This case emphasizes the clinical relevance of non-type b Hi meningitis and explores the diagnostic challenges, treatment considerations, and broader implications for neonatal infectious disease research.