Abstract
Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign lesion. This report presents the case of a middle-aged woman with asymptomatic SANT of the spleen, complicated by metastatic papillary thyroid carcinoma and an undiagnosed splenic mass. The condition was effectively managed through laparoscopic splenectomy, with a definitive diagnosis confirmed postoperatively. This case aims to contribute to enhancing the differential diagnosis of SANT by highlighting its radiological features, particularly in patients undergoing follow-up for malignancy.