Abstract
Food Safety Commission of Japan (FSCJ) hosted a symposium entitled "Concept of Integrated Approaches to Testing and Assessment (IATA) Using New Approach Methods (NAMs) -Learning from the Study of Thyroid Hormone System and Developmental Neurotoxicity-" to deepen our understanding on the application of NAMs through practical examples. The symposium took place at FSCJ meeting room (Akasaka, Minato-ku, Tokyo) on December 5th, 2024, attracting a total of 21 on-site attendees as well as 153 online participants. FSCJ Chairperson Dr. YAMAMOTO gave an opening remark. In the presentation 1, Dr. AKAHORI Yumi from the Chemicals Evaluation and Research Institute, Japan (CERI), who also serves as a member of FSCJ's Working Group on Assessment Methodology Development, presented a lecture titled "International Activities Related to NAMs." In the presentation 2, Dr. Mary Gilbert from the US EPA gave a lecture titled "Thyroid Disruption and Neurodevelopment in an Adverse Outcome Framework Translating NAMs- Filling in Gaps." In the Q&A session, participants discussed about the concept and definition of NAMs. In concluding the seminar, Dr. ASANO remarked that, given the active efforts to leverage NAMs abroad led by Europe and the US, FSCJ will continue to discuss various NAMs which would be accumulated internationally and their potential applications.