Does Intra-Operative Posterior Facet Steroid Injection in Lumbar Laminectomy Decreases Post-Operative Low Back Pain? A randomized Clinical Trial

腰椎椎板切除术中术中后关节面类固醇注射能否减轻术后腰痛?一项随机临床试验

阅读:1

Abstract

OBJECTIVES: The complexity of low back pain, involving factors like nerve compression and facet arthritis, prompts exploration of additional interventions, such as facet joint steroid infiltration during laminectomy, to potentially enhance post-operative pain relief in spinal stenosis patients. METHODS: This is a multicenter prospective randomized study. Patients were randomly allocated into two groups, one receiving a 2-ml injection of 80mg/2ml methylprednisolone acetate into the facets intraoperatively (n=25), the other receiving no injection (n=25). The Oswestry Disability Index (ODI) and Numeric Rating Scale (NRS) were collected at baseline, and at 1 week, 1 month, and 3 months post-operatively. RESULTS: Fifty patients were included, 25 in the control group and 25 in the infiltration group. The ODI significantly improved from baseline (32.6 ± 8.6) at 7 days (25.1 ± 7.4), 1 month (19.8 ± 9.9) and 3 months (17.0 ± 10.9) post-operatively in both the control and infiltration group. The NRS significantly improved from baseline at 7 days (2.7 ± 1.9), 1 month (1.7 ± 2.5) and 3 months (1.5 ± 2.5) post-operatively in both groups. No statistically significant difference was noted in ODI or NRS between the two groups at baseline or any of the follow-up timepoints. CONCLUSION: Our research indicates that combining steroid infiltration of the facet joints with simple laminectomy does not provide significant advantages beyond possibly expediting recovery. Studies with larger sample sizes are needed to reach the best conclusions for patients with lumbar spinal stenosis.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。