Abstract
INTRODUCTION: The use of "Platelet-Rich Fibrin (PRF)" has gained significant attention in maxillofacial surgery for its potential to accelerate healing. This trial aims to evaluate the effectiveness of PRF in improving postoperative recovery in subjects undergoing maxillofacial surgery. METHODS: In this double-blind trial, subjects were randomly assigned to either the PRF batch or the control batch. Key parameters assessed included wound healing, pain levels, soft tissue regeneration, and postoperative complications. Statistical analysis was conducted to evaluate the effectiveness of PRF using appropriate tests, with significance set at P < 0.05. RESULTS: Subjects in the PRF batch demonstrated faster wound healing (P = 0.03) and reduced pain levels compared to the control batch. Complications such as dry socket and infection were also significantly lower in the PRF batch (P < 0.01). The analysis indicated that PRF significantly enhances tissue regeneration and reduces postoperative complications. CONCLUSION: Platelet-rich fibrin is effective in accelerating healing post-maxillofacial surgery, with improved clinical outcomes and lower complication rates compared to conventional treatment methods.