A Case of Merkel Cell Carcinoma of Unknown Primary Origin Presenting With High Merkel Cell Polyomavirus DNA Levels in Swabs Obtained From the Normal Skin

一例原发灶不明的默克尔细胞癌,其正常皮肤拭子中默克尔细胞多瘤病毒DNA水平较高

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Abstract

Merkel cell carcinoma is a rare neuroendocrine tumor with high mortality. It is well known that clonal integration of the Merkel cell polyomavirus into the dermal precursor cells is a hypothesized pathway in Merkel cell carcinoma pathogenesis. Here, we demonstrate a case of Merkel cell carcinoma (primary origin unknown) presenting with high Merkel cell polyomavirus DNA levels in swabs obtained from normal skin.

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