Abstract
Recently, the continuous advancement of endoscopic technology has led to the widespread application of endoscopic full-thickness resection (EFTR) in clinical practice. The crucial aspect of EFTR is the successful closure of the wound. Initially, endoscopic clip and nylon thread suturing was employed; subsequently, a variety of innovative suturing techniques based on that have been developed, driving ongoing technological innovation in this field. Given the unique characteristics of EFTR, an increasing number of specialized endoscopic suturing devices are being explored. This article aims to systematically evaluate the efficacy, limitations, and clinical applicability of current endoscopic closure techniques for EFTR-induced defects.