Abstract
Inflammatory polyposis colitis is a rare, non-hereditary gastrointestinal disorder characterized by chronic diarrhea, diffuse gastrointestinal polyposis, and systemic features such as hypoalbuminemia, weight loss, and dermatological changes. The etiology remains unknown, with diagnosis reliant on clinical, endoscopic, and histopathological findings. This case describes a 79-year-old male with inflammatory polyposis colitis who responded to corticosteroid therapy. The report emphasizes the diagnostic and therapeutic challenges of this condition.