The Potential of the Alpha4 Beta7 Integrin Inhibitors as Treatment for Inflammatory Bowel Diseases and Related Disorders

α4β7整合素抑制剂在治疗炎症性肠病及相关疾病中的应用潜力

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Abstract

The invention in this patent application relates to compounds having structures represented generally herein by formula 1. These compounds are modulators of alpha 4 beta 7 integrin and may provide useful treatment for several inflammatory conditions such as inflammatory bowel diseases, including ulcerative colitis and Crohn's disease.

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