Dexamethasone decreases the transmesothelial electrical resistance of the parietal and visceral pleura
地塞米松降低壁层胸膜和脏层胸膜的跨间皮电阻
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作者:Sotirios Zarogiannis, Triantafyllia Deligiorgi, Ioannis Stefanidis, Vassilios Liakopoulos, Konstantinos Gourgoulianis, Paschalis Adam Molyvdas, Chrissi Hatzoglou
Abstract
The effect of dexamethasone on the transmesothelial electrical resistance (R(TM)) of sheep pleura was investigated by Ussing chamber experiments. Our results show that dexamethasone decreases the R(TM) of sheep pleurae, in part by stimulation of glucocorticoid receptors. This finding may be of importance in regard to the faster resolution of corticosteroid-treated pleural effusions.
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