Community exposure to perfluorooctanoate: relationships between serum concentrations and exposure sources

全氟辛酸酯的社区暴露:血清浓度与暴露源之间的关系

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作者:Edward Anthony Emmett, Frances Susan Shofer, Hong Zhang, David Freeman, Chintan Desai, Leslie Michael Shaw

Conclusions

Residential water source was the primary determinant of serum (PFOA).

Methods

The authors conducted questionnaire and serum PFOA measurements in a stratified random sample and volunteers residing in locations with the same residential water supply but with higher and lower potential air PFOA exposure.

Objective

The objective of this study was to determine serum (perfluorooctanoate [PFOA]) in residents near a fluoropolymer production facility: the contributions from air, water, and occupational exposures, personal and dietary habits, and relationships to age and gender.

Results

Serum (PFOA) greatly exceeded general population medians. Occupational exposure from production processes using PFOA and residential water had additive effects; no other occupations contributed. Serum (PFOA) depended on the source of residential drinking water, and not potential air exposure. For public water users, the best-fit model included age, tap water drinks per day, servings of home-grown fruit and vegetables, and carbon filter use. Conclusions: Residential water source was the primary determinant of serum (PFOA).

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