Evaluation of serological response to foot-and-mouth disease vaccination in BLV infected cows

评估感染 BLV 的奶牛对口蹄疫疫苗接种的血清学反应

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作者:Rodrigo Puentes, Laureana De Brun, Agustina Algorta, Valeria Da Silva, Florencia Mansilla, Gustavo Sacco, Silvia Llambí, Alejandra V Capozzo

Background

Bovine Leukemia Virus (BLV) produces disorders on the immune system in naturally infected animals, which may counteract the development of immunity after vaccination. The

Conclusions

Cattle infected with BLV at the time of immunization may elicit a low-magnitude serological response to a commercial Foot-and-mouth disease vaccine.

Results

Total anti-A24/Cruzeiro antibodies, IgM, IgG1, IgG2 titers and avidity index of specific antibodies were determined by ELISA. Although only marginally significant differences were found between groups in terms of total antibodies, anti-FMD IgM and IgG1 titers were significantly lower in heifers infected with BLV at the 15 dpv (p < 0.01). Animals that became infected during the study did not show differences to the BLV negative group. Conclusions: Cattle infected with BLV at the time of immunization may elicit a low-magnitude serological response to a commercial Foot-and-mouth disease vaccine.

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