Bacterial-Type Long-Chain Polyphosphates Bind Human Proteins in the Phosphatidylinositol Signaling Pathway
细菌型长链多磷酸盐在磷脂酰肌醇信号通路中与人类蛋白质结合
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作者：Viola Krenzlin, Julian Roewe, Marcel Strueve, María Martínez-Negro, Arjun Sharma, Christoph Reinhardt, Svenja Morsbach, Markus Bosmann
Abstract
A human proteome microarray was probed with long-chain polyphosphates. Several of the identified proteins (DAB1, PIP4K2B) were further validated using small-scale assays. The depicted proteins shared the common feature of a functional relationship to the PI3K/Akt signaling pathway.
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