Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer

人类血清中的 Gastrokine 1 mRNA 不是胃癌的有用生物标志物

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作者:Valentina Villano, Chiara Stella Di Stadio, Antonella Federico, Filomena Altieri, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa, Paolo Arcari

Background

We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.

Conclusions

Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.

Results

Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals. Conclusions: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.

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