Interlaboratory studies and initiatives developing standards for proteomics

制定蛋白质组学标准的实验室间研究和举措

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作者:Alexander R Ivanov, Christopher M Colangelo, Craig P Dufresne, David B Friedman, Kathryn S Lilley, Karl Mechtler, Brett S Phinney, Kristie L Rose, Paul A Rudnick, Brian C Searle, Scott A Shaffer, Susan T Weintraub

Abstract

Proteomics is a rapidly transforming interdisciplinary field of research that embraces a diverse set of analytical approaches to tackle problems in fundamental and applied biology. This viewpoint article highlights the benefits of interlaboratory studies and standardization initiatives to enable investigators to address many of the challenges found in proteomics research. Among these initiatives, we discuss our efforts on a comprehensive performance standard for characterizing PTMs by MS that was recently developed by the Association of Biomolecular Resource Facilities (ABRF) Proteomics Standards Research Group (sPRG).

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