A Deep Insight into the Sialome of Rhodnius neglectus, a Vector of Chagas Disease

深入了解查加斯病媒介 Rhodnius ignores 的唾液腺

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作者:Paula Beatriz Santiago, Teresa C F Assumpção, Carla Nunes de Araújo, Izabela Marques Dourado Bastos, David Neves, Ionizete Garcia da Silva, Sébastien Charneau, Rayner Myr L Queiroz, Tainá Raiol, João Victor de Araújo Oliveira, Marcelo Valle de Sousa, Eric Calvo, José M C Ribeiro, Jaime M Santana

Background

Triatomines are hematophagous insects that act as vectors of Chagas disease. Rhodnius neglectus is one of these kissing bugs found, contributing to the transmission of this American trypanosomiasis. The saliva of hematophagous arthropods contains bioactive molecules responsible for counteracting host haemostatic, inflammatory, and immune responses.

Significance

The data presented improve our understanding of hematophagous arthropod sialomes, and aid in understanding hematophagy and the complex interplay among vectors and their vertebrate hosts.

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