Modified Polyacrylic Acid-Zinc Composites: Synthesis, Characterization and Biological Activity

改性聚丙烯酸-锌复合材料的合成、表征及生物活性

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作者:Mohammed Rafi Shaik, Mufsir Kuniyil, Mujeeb Khan, Naushad Ahmad, Abdulrahman Al-Warthan, Mohammed Rafiq H Siddiqui, Syed Farooq Adil

Abstract

Polyacrylic acid (PAA) is an important industrial chemical, which has been extensively applied in various fields, including for several biomedical purposes. In this study, we report the synthesis and modification of this polymer with various phenol imides, such as succinimide, phthalimide and 1,8-naphthalimide. The as-synthesized derivatives were used to prepare polymer metal composites by the reaction with Zn(+2). These composites were characterized by using various techniques, including NMR, FT-IR, TGA, SEM and DSC. The as-prepared PAA-based composites were further evaluated for their anti-microbial properties against various pathogens, which include both Gram-positive and Gram-negative bacteria and different fungal strains. The synthesized composites have displayed considerable biocidal properties, ranging from mild to moderate activities against different strains tested.

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