Safety Evaluation of Carbon Dots in UM-UC-5 and A549 Cells for Biomedical Applications
碳点在 UM-UC-5 和 A549 细胞中的生物医学应用安全性评估
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作者：Carla M Magalhães, Eduarda Ribeiro, Sónia Fernandes, Joaquim Esteves da Silva, Nuno Vale, Luís Pinto da Silva
| 期刊： | Cancers | 影响因子： | |
| 时间： | 2024 | 起止号： | 2024 Sep 29;16(19):3332. |
| doi： | 10.3390/cancers16193332 | 研究方向： | 免疫、细胞生物学 |
| 细胞类型： | 其它细胞 | |
Methods
We synthesized four N-doped CDs through a hydrothermal method. Cell viability assays were conducted on A549 and UM-UC-5 cancer cells at a range of concentrations and incubation times, both individually and with the chemotherapeutic agent 5-fluorouracil (5-FU).
Results
The obtained results suggest that the newly developed CDs exhibit suitability for applications such as bioimaging, as no significant impact on cell viability was observed for CDs alone.
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