Background
The
Conclusions
It was concluded that the osteogenic potential was greater in BM-MSCs than AD-MSCs when extracted from young dogs.
Results
MTT conversion was greater in BM-MSCs compared to AD-MSCs after 14 and 21 days of differentiation; ALP activity was greater in differentiated AD-MSCs on day 7; collagen synthesis was greater in BM-MSCs on days 14 and 21; the percentage of mineralized area per field was greater in BM-MSCs compared to AD-MSCs; osterix expression was greater in BM-MSCs in days 14 and 21, and BSP and OC expression levels were greater in BM-MSCs at all the investigation time-points. Conclusions: It was concluded that the osteogenic potential was greater in BM-MSCs than AD-MSCs when extracted from young dogs.