The complex of immunoglobulin A and uromodulin as a diagnostic marker for immunoglobulin A nephropathy

免疫球蛋白 A 和尿调节蛋白复合物作为免疫球蛋白 A 肾病的诊断标志物

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作者:Takashi Obara, Sadaaki Mizoguchi, Yasunori Shimozuru, Toshitaka Sato, Osamu Hotta

Background

The only tool to diagnose immunoglobulinn A nephropathy (IgAN) is renal biopsy which requires hospitalization; moreover, renal biopsy has a risk of critical bleeding. Therefore, a non-invasive method for accurate diagnosis of IgAN is desirable and a must-to-have tool for the clinics. For this

Conclusion

Detection of the urinary IgA-uromodulin complex by ELISA is a useful non-invasive method to diagnose IgAN.

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