Secondary metabolites from the soft coral Sinularia arborea

软珊瑚 Sinularia arborea 的次生代谢产物

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作者:Kuan-Hua Chen, Chang-Feng Dai, Mei-Chin Lu, Jan-Jung Li, Jih-Jung Chen, Yu-Chia Chang, Yin-Di Su, Wei-Hsien Wang, Ping-Jyun Sung

Abstract

Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia.

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