Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides

银纳米粒子与膜通透性抗菌肽之间的协同作用

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作者:Serge Ruden, Kai Hilpert, Marina Berditsch, Parvesh Wadhwani, Anne S Ulrich

Abstract

Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects between polymyxin B and silver nanoparticles for gram-negative bacteria.

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