High frequency of Chlamydia pneumoniae and risk factors in children with acute respiratory infection

急性呼吸道感染患儿肺炎衣原体感染率高及危险因素

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作者:Matheus Silva Alves, Marilha da Silva Cariolano, Hivylla Lorrana Dos Santos Ferreira, Elen Sousa de Abreu Silva, Karen Karollynny Pereira Felipe, Silvio Gomes Monteiro, Eduardo Martins de Sousa, Afonso Gomes Abreu, Lee Ann Campbell, Michael E Rosenfeld, Mario Hiroyuki Hirata, Rosario Dominguez Cresp

Conclusion

Taken together, these results revealed a high frequency of C. pneumoniae in both children with URTI and CAP.

Results

Positivity for C. pneumoniae DNA was higher in samples from URTI children (38.2%) and from CAP children (18.0%) than in those from the control group (7.9%; p < 0.001). Moreover, C. pneumoniae DNA was denser in children with URTI than in asymptomatic children. Considering the cutoff, the highest value of C. pneumoniae DNA found in asymptomatic children of the 3.98 log10 copies/mL, 8.5% (14/165) of the children with URTI, and 3.3% (5/150) with CAP presented high copy numbers of C. pneumoniae DNA.

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