Time course study of Paenarthrobacter nicotinovorans secondary metabolite toxicity profile

In previous studies , Paenarthrobacter nicotinovorans was isolated and screened for antimicrobial activity. Further, secondary metabolites were isolated and screened for antimicrobial activity and cytotoxicity in vitro . The current study determines if increased exposure of Hela cells to the secondary metabolites over time increases the cytotoxicity. The results show no detectable increase of cytotoxicity in HeLa cells.