Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation
易功散对小鼠急性炎症模型铁稳态的影响
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作者：Qin Zheng, Yu Guan, Lemin Xia, Zhicheng Wang, Yiling Jiang, Xiaofeng Zhang, Jianying Wang, Guohua Wang, Yiqiong Pu, Jing Xia, Meihong Luo
Abstract
We investigated the effect of Yi Gong San (YGS) decoction on iron homeostasis and the possible underlying mechanisms in a mouse model of acute inflammation in this study. Our findings suggest that YGS regulates iron homeostasis by downregulating the level of HAMP mRNA, which may depend on regulation of the IL-6/STAT3 or BMP/HJV/SMAD pathway during acute inflammation.
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