Porous Titanium Scaffolds Fabricated by Metal Injection Moulding for Biomedical Applications

采用金属注射成型技术制造的多孔钛支架可用于生物医学应用

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作者:Ali Dehghan-Manshadi, Yunhui Chen, Zhiming Shi, Michael Bermingham, David StJohn, Matthew Dargusch, Ma Qian

Abstract

Biocompatible titanium scaffolds with up to 40% interconnected porosity were manufactured through the metal injection moulding process and the space holder technique. The mechanical properties of the manufactured scaffold showed a high level of compatibility with those of the cortical human bone. Sintering at 1250 °C produced scaffolds with 36% porosity and more than 90% interconnected pores, a compressive yield stress of 220 MPa and a Young's modulus of 7.80 GPa, all suitable for bone tissue engineering. Increasing the sintering temperature to 1300 °C increased the Young's modulus to 22.0 GPa due to reduced porosity, while reducing the sintering temperature to 1150 °C lowered the yield stress to 120 MPa, indicative of insufficient sintering. Electrochemical studies revealed that samples sintered at 1150 °C have a higher corrosion rate compared with those at a sintering temperature of 1250 °C. Overall, it was concluded that sintering at 1250 °C yielded the most desirable results.

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