Fabrication of Size-Tunable Metallic Nanoparticles Using Plasmid DNA as a Biomolecular Reactor

利用质粒 DNA 作为生物分子反应器制造尺寸可调的金属纳米粒子

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作者:Jacopo Samson, Irene Piscopo, Alex Yampolski, Patrick Nahirney, Andrea Parpas, Amit Aggarwal, Raihan Saleh, Charles Michael Drain

Abstract

Plasmid DNA can be used as a template to yield gold, palladium, silver, and chromium nanoparticles of different sizes based on variations in incubation time at 70 °C with gold phosphine complexes, with the acetates of silver or palladium, or chromium acetylacetonate. The employment of mild synthetic conditions, minimal procedural steps, and aqueous solvents makes this method environmentally greener and ensures general feasibility. The use of plasmids exploits the capabilities of the biotechnology industry as a source of nanoreactor materials.

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