Physiological effect of iron status on patients with polycystic ovary syndrome in Basrah city

铁状态对巴士拉市多囊卵巢综合征患者的生理影响

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作者:Dalal F Al-Akabi, Hanadi A Hafth

Abstract

Abstract in English, Serbian Polycystic ovary syndrome (PCOS) is one of the most common gynecological diseases that affect the fertility in women in Basra governorate. The current study was designed in order to assess iron aberrations in PCOS patients by measuring the related parameters and their relationship with sex hormones in patients with PCOS. Serum samples were collected from 45 PCOS patients and 45 controls from a private women's clinic and were measured by ELISA in a private medical laboratory. The results showed a significant decrease in the level of hepcidin, transferrin and estradiol versus a significant increase in iron, ferritin, progesterone and testosterone. The current study showed a clear imbalance in the level of iron and its serum regulating parameters in in PCOS women, and there is an effective correlation between iron status and sex hormones. Sindrom policističnih jajnika (PCOS) je jedno od najčešćih ginekoloških bolesti koje utiču na plodnost žena u provinciji Basra. Sadašnja studija je dizajnirana da proceni aberacije gvožđa kod pacijenata sa PCOS merenjem povezanih parametara i njihovog odnosa sa polnim hormonima kod pacijenata sa PCOS. Uzorci seruma su prikupljeni od 45 pacijenata sa PCOS-om i 45 kontrola iz privatne ženske klinike i mereni su ELISA testom u privatnoj medicinskoj laboratoriji. Rezultati su pokazali značajno smanjenje nivoa hepcidina, transferina i estradiola naspram značajnog povećanja gvožđa, feritina, progesterona i testosterona. Sadašnja studija je pokazala jasnu neravnotežu u nivou gvožđa i njegovih serumskih regulacionih parametara kod žena sa PCOS-om, i postoji efikasna korelacija između statusa gvožđa i polnih hormona.

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