Reduction of venous pressure during the resection of liver metastases compromises enteric blood flow: IGFBP-1 as a novel biomarker of intestinal barrier injury
肝转移瘤切除术中静脉压降低影响肠道血流：IGFBP-1 作为肠道屏障损伤的新型生物标志物
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作者：Hermes Vieira Barbeiro, Marcel Autran César Machado, Heraldo Possolo de Souza, Fabiano Pinheiro da Silva, Marcel Cerqueira César Machado
Conclusion
We propose the use of insulin-like growth factor binding protein-1 as a novel biomarker of intestinal damage in such situations.
Methods
We investigated intestinal fatty-acid binding protein and insulin-like growth factor binding protein levels in the plasma of patients who underwent liver resection.
Results
We show that liver resection is associated with significant intestinal barrier injury, even if the Pringle maneuver is not performed.
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