Dispersive viscosurgical devices demonstrate greater efficacy in protecting corneal endothelium in vitro

分散性粘液外科装置在体外保护角膜内皮方面表现出更高的功效

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作者:Timur Mert Yildirim, Gerd U Auffarth, Hyeck-Soo Son, Ramin Khoramnia, Donald John Munro, Patrick R Merz

Conclusion

Dispersive OVDs from this study showed greater adherence to the endothelial surface than the cohesive ones. Furthermore, postoperative endothelial cell counts of corneas treated with dispersive OVDs were higher than of corneas treated with cohesive OVDs. Our in vitro results suggest that dispersive OVDs protect the corneal endothelium better during phacoemulsification than cohesive OVDs.

Objective

During phacoemulsification, the corneal endothelium is protected by an ophthalmic viscosurgical device (OVD). In this in vitro study, we assessed six different OVDs for their effectiveness in protecting the corneal endothelium.

Results

The least postoperative endothelial coating and cell count were observed in the cohesive OVDs while the dispersive OVDs showed statistically significant higher values. Healon EndoCoat and Viscoat yielded a coating area of 86 (85-92)% and 85 (85-90)%, respectively. Endothelial cell count was highest in the two dispersive groups with 4065 (3928-4088) cells/mm2 (Methylvisc) and 4032 (4015-4115) cells/mm2 (Viscoat). Endothelial coating area and endothelial cell count correlated statistically significantly.

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