HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region

巴西马瑙斯的 HTLV-2 感染:首次在西亚马逊地区的城市地区描述 HTLV-2c 亚型

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作者:Gemilson Soares Pontes, Hygor Halyson Figueiredo Ribeiro, Diana Mota Toro, José Pereira de Moura Neto, Victor Souza, Maria Edilene Martins de Almeida, Valdinete Alves do Nascimento, Cristovão Alves da Costa, Felipe Gomes Naveca, Mike Santos, Antonio Carlos Rosário Vallinoto

Conclusions

This study describes the first known occurrence of HTLV-2c in the urban area of Brazil's western Amazon region.

Methods

Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region.

Results

A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype. Conclusions: This study describes the first known occurrence of HTLV-2c in the urban area of Brazil's western Amazon region.

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