Salvaging of severely ruptured living-related renal allograft secondary to acute antibody mediated rejection

因急性抗体介导排斥反应而导致活体肾移植严重破裂的抢救

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作者:Mohamad Almarastani, Noura Aloudah, Mohammad Hamshow, Bassem Hegab, Khaled O Alsaad

Conclusion

With modern immunosuppression therapy and proven surgical procedures, the efficacy of salvaged renal grafts and graft survival rates may improve substantially.

Discussion

Observations arising from this case are: (1) RAR caused by rejection is still encountered in clinical practice despite effective immunosuppressive management; (2) the severity of the histopathological features of rejection does not necessarily correlate with the extent of graft rupture; and (3) salvaging the graft should be attempted whenever possible as current immunosuppression and advances in surgical techniques may have an impact on long-term graft function and survival, differing from those previously published. Conclusion: With modern immunosuppression therapy and proven surgical procedures, the efficacy of salvaged renal grafts and graft survival rates may improve substantially.

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