Combination of platelet-rich plasma and stromal vascular fraction on the level of transforming growth factor-β in rat subjects experiencing deep dermal burn injury

富血小板血浆和基质血管成分的组合对深度皮肤烧伤大鼠转化生长因子-β水平的影响

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作者:Sachraswaty Rachman Laidding, Fonny Josh, Francisca, Muhammad Faruk, Andi Sinapati Palissei, Bayu Satria, Warsinggih, Agussalim Bukhari, Muh Nassrum Massi, Andi Asadul Islam

Conclusion

The combination of SVFs and PRP increases the level of TGF-β in the healing process of deep dermal burns.

Methods

This was an experimental study in 64 rats using a post-test control group design consisting of 1 group of SVFs and PRP combination injection treatment group, 1 group given a topical combination of SVFs and PRP, 1 group given Vaseline, and 1 control group.

Results

There was a significant difference in TGF-β levels between the deep dermal burns group that was given a combination of SVFs and PRP injection and topical, the Vaseline group, and the control group with p-value <0.05.

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