Correlations between Fatty Acid Profile and Body Fat Distribution in Postmenopausal Women-A Cross Sectional Study

绝经后妇女脂肪酸谱与体脂分布的相关性——一项横断面研究

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作者:Anna Maria Cybulska, Kamila Rachubińska, Karolina Skonieczna-Żydecka, Arleta Drozd, Jolanta Pawlik, Ewa Stachowska, Aneta Cymbaluk-Płoska, Elżbieta Grochans

Abstract

The aim of the study was to assess the fatty acid profile of the whole blood of postmenopausal women, taking into account anthropometric parameters. The study involved 156 healthy women with an average age of 60 (SD = 6.3 years) years who were living in the West Pomerania Province (Poland). An original questionnaire was presented to all patients, conducting anthropometric measurements of them: weight, height, waist and hip circumference, body mass index (BMI), waist-hip ratio (WHR) and body adipose index (BAI), as well as an assessment of the fatty acid profile by employing gas chromatography. It has been observed that in menopausal women, the concentration of C16:1 increases with respect to their BMI (r = 0.205 p = 0.01). Similar correlations were noted with regard to body weight (C16:1 r = 0.177 p = 0.029). It was also shown that the concentration of C18trans11 (r = -0.166 p = 0.039), 18:2n6 (r = -0.165 p = 0.04) and n6/n9 (r = -0.194 p = 0.015) were negatively correlated with respect to their WHR, while the levels C16:1 (r = 0.22 p = 0.006), C18:1n9 (r = 0.22 p = 0.007), C24:1 (r = 0.251 p = 0.002), MUFA (r = 0.227 p = 0.046) and n9 (r = 0.224 p = 0.005) were correlated positively with respect to their BAI. The fatty acid profile of the whole blood of postmenopausal women is modulated to a poor extent by anthropometric variables. Therefore, more prospective research is warranted.

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