Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report

肾移植患者棘阿米巴致死性肉芽肿性阿米巴脑炎:病例报告

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作者:Ahmad Salameh, Nancy Bello, Jennifer Becker, Tirdad Zangeneh

Abstract

Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pentamidine, sulfadiazine, fluconazole, flucytosine, and azithromycin.

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