The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes

有氧阻力训练和西兰花补充对 2 型糖尿病男性血浆 Dectin-1 和胰岛素抵抗的影响

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作者:Ayoub Saeidi, Mohammad Soltani, Ali Daraei, Hanieh Nohbaradar, Marjan Mosalman Haghighi, Nikoo Khosravi, Kelly E Johnson, Ismail Laher, Anthony C Hackney, Trisha A VanDusseldorp, Hassane Zouhal0

Background

This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D).

Conclusion

The combination of CARET and broccoli supplementation produced the largest improvements in insulin resistance and dectin-1 and other complications of T2D.

Methods

Forty-four males with T2D were randomly allocated to four groups (n = 11 each group): CARET + broccoli supplement (TS), CARET + placebo (TP), control + broccoli supplement (S), and control + placebo (CP). CARET was performed three days per week for 12 weeks. TS and S groups received 10 g of broccoli supplement per day for 12 weeks. All variables were assessed at baseline and 12 weeks.

Results

Plasma dectin-1 levels were decreased in TS and TP groups compared with the CP group (p < 0.05). Cardiometabolic risk factors showed significant reductions in TP and TS groups compared to S and CP groups (p < 0.05).

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