日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Employing multiple synchronous outcome samples per subject to improve study efficiency

采用每个受试者多个同步结果样本以提高研究效率

A'Hern, Roger P

Real-time imaging of single neuronal cell apoptosis in patients with glaucoma

青光眼患者单神经元细胞凋亡的实时成像

Cordeiro, Maria F; Normando, Eduardo M; Cardoso, M Jorge; Miodragovic, Serge; Jeylani, Seham; Davis, Benjamin M; Guo, Li; Ourselin, Sebastien; A'Hern, Roger; Bloom, Philip A

A phase II trial to assess the activity of gemcitabine and docetaxel as first line chemotherapy treatment in patients with unresectable leiomyosarcoma

一项评估吉西他滨和多西他赛作为一线化疗方案治疗不可切除平滑肌肉瘤患者的II期临床试验

Seddon, Beatrice; Scurr, Michelle; Jones, Robin L; Wood, Zoe; Propert-Lewis, Cerys; Fisher, Cyril; Flanagan, Adrienne; Sunkersing, Jonanthan; A'Hern, Roger; Whelan, Jeremy; Judson, Ian

Biomarker changes associated with the development of resistance to aromatase inhibitors (AIs) in estrogen receptor-positive breast cancer

雌激素受体阳性乳腺癌中与芳香化酶抑制剂(AIs)耐药性发展相关的生物标志物变化

Arnedos, M; Drury, S; Afentakis, M; A'Hern, R; Hills, M; Salter, J; Smith, I E; Reis-Filho, J S; Dowsett, M

Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance

微阵列基因特征的预测性能:肿瘤异质性和多种耐药机制的影响

Ng, Charlotte K Y; Weigelt, Britta; A'Hern, Roger; Bidard, Francois-Clement; Lemetre, Christophe; Swanton, Charles; Shen, Ronglai; Reis-Filho, Jorge S

Enhanced expression of the PDGFR/Abl signaling pathway in aromatase inhibitor-resistant breast cancer

芳香化酶抑制剂耐药乳腺癌中PDGFR/Abl信号通路表达增强

M T Weigel, S Banerjee, M Arnedos, J Salter, R A'Hern, M Dowsett, L A Martin

Mutation profiling of adenoid cystic carcinomas from multiple anatomical sites identifies mutations in the RAS pathway, but no KIT mutations

对来自多个解剖部位的腺样囊性癌进行突变谱分析,发现RAS通路存在突变,但未发现KIT突变。

Wetterskog, Daniel; Wilkerson, Paul M; Rodrigues, Daniel N; Lambros, Maryou B; Fritchie, Karen; Andersson, Mattias K; Natrajan, Rachael; Gauthier, Arnaud; Di Palma, Silvana; Shousha, Sami; Gatalica, Zoran; Töpfer, Chantal; Vukovic, Vesna; A'Hern, Roger; Weigelt, Britta; Vincent-Salomon, Anne; Stenman, Göran; Rubin, Brian P; Reis-Filho, Jorge S

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo

体外和体内研究临床活性 mTORC1 抑制剂依维莫司联合他莫昔芬或来曲唑的有效性和分子相互作用

Martin, Lesley-Ann; Pancholi, Sunil; Farmer, Ian; Guest, Stephanie; Ribas, Ricardo; Weigel, Marion T; Thornhill, Allan M; Ghazoui, Zara; A'Hern, Roger; Evans, Dean B; Lane, Heidi A; Johnston, Stephen R; Dowsett, Mitch

Immunophenotypic and genomic characterization of papillary carcinomas of the breast

乳头状癌的免疫表型和基因组特征分析

Duprez, Raphaëlle; Wilkerson, Paul M; Lacroix-Triki, Magali; Lambros, Maryou B; MacKay, Alan; A'Hern, Roger; Gauthier, Arnaud; Pawar, Vidya; Colombo, Pierre-Emanuel; Daley, Frances; Natrajan, Rachael; Ward, Eric; MacGrogan, Gaëtan; Arbion, Flavie; Michenet, Patrick; Weigelt, Britta; Vincent-Salomon, Anne; Reis-Filho, Jorge S

A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

对 BRCA1 突变型雌激素受体阴性和阳性乳腺癌进行全基因组大规模平行测序分析

Natrajan, Rachael; Mackay, Alan; Lambros, Maryou B; Weigelt, Britta; Wilkerson, Paul M; Manie, Elodie; Grigoriadis, Anita; A'Hern, Roger; van der Groep, Petra; Kozarewa, Iwanka; Popova, Tatiana; Mariani, Odette; Turaljic, Samra; Furney, Simon J; Marais, Richard; Rodruigues, Daniel-Nava; Flora, Adriana C; Wai, Patty; Pawar, Vidya; McDade, Simon; Carroll, Jason; Stoppa-Lyonnet, Dominique; Green, Andrew R; Ellis, Ian O; Swanton, Charles; van Diest, Paul; Delattre, Olivier; Lord, Christopher J; Foulkes, William D; Vincent-Salomon, Anne; Ashworth, Alan; Stern, Marc Henri; Reis-Filho, Jorge S